Today about 150 million men have problems with erection all over the world. In opinion of experts, the Cialis usage will help them to solve this problem and to adjust a normal sexual life. Appearance of a new highly effective drug undoubtedly will force many men to begin treatment. Cialis has already well proved in the Europe, Australia and New Zealand. The Great Britain, Denmark, Finland, Sweden and Germany are the countries where this medicine was used the first time. "Cialis works effectively more than one day, and it opens unique opportunities in therapy of erectile dysfunctions, allowing men with this problem to normalize their sexual life " - Richard Pilnik, the president of Eli Lilly, European division, has declared. " For men much of 31 million in the Europe, suffering erectile dysfunction, Cialis becomes the cardinal solving of a problem " - says Paul Clark, the Executive Director ICOS. Cialis is intended for treatment of erectile dysfunction of any degree of severity. It is recommended to take a doze of 20 mg before sexual activity, irrespective of eating any meal or drinking alcohol. Cialis concerns to a inhibitor class of phosphodiesterase-5 enzyme. It works based on selective and effective blockade of phosphodiesterase-5, and promotes a relaxation of lissosphincter cells and increasing a blood flow in a penis. At present time Cialis is a unique inhibitor of phosphodiesterase-5 which keeps its effect more than a day (up to 36 hours). Thus it is important to note, that erection is occurred only when a person is sexually stimulated. It will allow partners to avoid planning of their sexual activities and to go on their normal rhythm of life. Taking drug in the morning you can take the advantage of its effect in the evening. As well as for all medicines of this class, a strong contraindication for Cialisa is taking the drug together with the nitrates used at therapy of cardiovascular diseases. By the current moment over 4000 men participated in more than 60 clinical researches which have proved efficiency and safety of this medicine. Cialis has improved erectile function at 81 % of men and has shown good tolerance. The drug has shown high efficiency at patients of all age.