NIA 24 Skin Strengthening Complex contains "Pro-NAD" which was specifically designed to enable the niacin to be effectively converted in your skin cells to its active form- "nicotinamide adenine dinucleotide" or "NAD". Pro NAD was chosen by the National Cancer Institute of the National Institutes of Health for development as a new skin cancer prevention treatment. NIA 24 Skin Strengthening Complex made with Pro Nad does not cause skin irritation or sensitivity. NIA 24 products will also work with other popular products and skin care programs, to help promote better results. NIA 24 has been clinically shown to improve skin texture, tone and hyper pigmentation. NIA 24 is Niacin based and backed by 25 years of research plus is one of the leading skin care treatments available in the market today. Niacin helps to build healthier, stronger skin and reduces the appearance of fine lines, wrinkles associated with sun damage and aging. Niacin, once converted to its active form, NAD, helps to maintain the integrity of your skin cells and allows 24/7 delivery to skin with effective levels of niacin that will help the look and feel of your skin. Nia 24 Skin Strengthening Complex protects against and repairs skin damage that may have already occurred. The National Cancer Institute supports Nia 24 because the products will discourage the formation of skin cancer cells and can reverse damage that may lead to skin cancer. In NIA 24 clinical studies, users have seen dramatic results in as little as 90 days: 90 percent reduction in hyper pigmentation. 82 percent improved texture. 81 percent increased smoothness. 80 percent improved tone. 68 percent reduction of fine lines and wrinkles. 53 percent in skin firmness. Easy directions: Use NIA 24 Skin Strengthening Complex in the morning and throughout the day as needed. Apply a dime sized amount on your face and neck area. Should be used on clean skin or over a moisturizer. Apply prior to exposure to the suns harmful rays. Re-apply as needed after towel-drying swimming or perspiring. Avoid any contact with your eye area.